Brand Sovaldi by Gilead
Sofosbuvir by Myan

Sovaldi (Sofosbuvir)

5.00 out of 5
(2 customer reviews)


Brand Name: Sovaldi

Active Ingredient: Sofosbuvir

Strength: 400MG

Dosage Form: Oral Tablets

Indication: Chronic Hepatitis C Virus Infection

Manufacturer: Brand by: Gilead Sciences Inc.

                       Generic by: Mylan

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Product Description

What Is Sovaldi?

Sovaldi (sofosbuvir) is an antiviral medication that prevents hepatitis C virus (HCV) from multiplying in your body. Sovaldi is used in combination with other medications to treat hepatitis C in adults. Sofosbuvir is sometimes used in people who also have HIV, or people who have liver cancer and are going to have a liver transplant. This medicine is not a treatment for HIV or AIDS.

Sovaldi must be given in combination with other antiviral medications and should not be used alone. Sovaldi is usually given with ribavirin (Copegus, Rebetol, Ribasphere, RibaTab) with or without peginterferon alfa (Pegasys, PegIntron).Sovaldi is also used together with Daklinza (daclatasvir) to treat hepatitis C genotype 1,2,3,4 infections in adults. Sovaldi is used in combination with other medications, usually ribavirin with or without peginterferon alfa.

Before taking this medicine
You should not use Sovaldi you are allergic to sofosbuvir. To make sure Sovaldi is safe for you, tell your doctor if you have:

  • liver problems other than hepatitis, or if you have had a liver transplant;
  • kidney disease (or if you are on dialysis);
  • HIV (human immunodeficiency virus); or
  • if you have recently used a heart rhythm medicine called amiodarone (Cordarone, Pacerone).

Do not use sofosbuvir with ribavirin if you are pregnant, or if you are a man and your female sexual partner is pregnant.

  • If you are a woman, do not use Sovaldi with ribavirin if you are pregnant.
  • If you are a man, do not use this drug combination if your sexual partner is pregnant. An unborn baby could also be harmed if a man fathers the child while he is taking ribavirin.
  • Use at least 2 effective forms of non-hormonal birth control (condom, diaphragm with spermicide) while either sexual partner is using these medications together. Keep using 2 forms of birth control for at least 6 months after treatment ends. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using Sovaldi with ribavirin.
  • Ribavirin can cause birth defects or death in an unborn baby.
  • It is not known whether sofosbuvir passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How Should I Take Sovaldi?

Do not take Sovaldi as your only medication to treat hepatitis C. It must be used in combination with other antiviral medication. Your disease may become resistant if you do not take it in combination with other medicines your doctor has prescribed. Sovaldi is usually taken once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. You may take this medicine with or without food. Take the medicine at the same time each day. While using Sovaldi, you may need frequent blood tests. Sovaldi can be stored in the original container at room temperature away from moisture and heat.

Sovaldi dosing information
Usual Adult Dose for Chronic Hepatitis C: 400 mg orally once a day

Duration of Therapy:

  • Genotype 1 or 4 CHC: 12 weeks
  • Genotype 2 CHC: 12 weeks
  • Genotype 3 CHC: 24 weeks
  • Hepatocellular carcinoma awaiting liver transplantation: Up to 48 weeks or until time of liver transplantation (whichever occurs first)


  • Sofosbuvir should be used in combination with ribavirin with or without pegylated interferon or daclatasvir
  • Efficacy was established in patients with HCV genotype 1, 2, 3, or 4 infection, including patients with hepatocellular carcinoma meeting Milan criteria (awaiting liver transplantation) and HCV/HIV-1 coinfected patients.
  • Sovaldi and ribavirin therapy for 24 weeks can be considered for patients with genotype 1 CHC who cannot use an interferon-based regimen; treatment decision should be guided by benefits/risks assessment for the individual patient.
  • Sovaldi and ribavirin therapy is recommended for patients with hepatocellular carcinoma awaiting liver transplantation to prevent posttransplant HCV reinfection.

Approved indication: As a part of a combination antiviral treatment regimen, for the treatment of chronic hepatitis C infection.

Read the medication guide or patient instructions provided with each medication in your combination therapy. Do not change your doses or medication schedule without your doctor’s advice.

What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Do not take more than 400 milligrams of sofosbuvir in one day.

What happens if I overdose?
Seek emergency medical attention or call the local Poison Help line.

What should I avoid while taking Sovaldi?
Taking this medication will not prevent you from passing hepatitis C to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HCV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

Sovaldi Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction to Sovaldi: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have:

  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or
  • fever, swollen gums, painful mouth sores, skin sores, cold or flu symptoms, cough.

Common Sovaldi side effects may include:

  • headache, tired feeling;
  • mild itching;
  • nausea;
  • sleep problems (insomnia);

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Sovaldi, especially:

  • amiodarone;
  • John’s wort;
  • tipranavir;
  • seizure medication – carbamazepine, oxcarbazepine, phenobarbital, phenytoin; or
  • tuberculosis medication – rifabutin, rifampin, rifapentine.

This list is not complete. Other drugs may interact with sofosbuvir, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

For further information about buying Sovaldi (Sofosbuvir), please read the prescribing information and product monograph for those who wish to learn more.

2 reviews for Sovaldi (Sofosbuvir)

    5 out of 5


    glad to find sovaldi here, and thanks for the talk, appreciated!

    5 out of 5


    Thanks! my hep C is cured!!! The pharmacist and staff is wonderful. Their service and knowledge is above and beyond! Thank you!

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