The study “Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis,” was recently published in the journal Thorax. The researchers in this study compiled patient outcome data from all of the previous 3 major clinical trials on pirfenidone, the two CAPACITY trials and the ASCEND trial.
The combined patient data was analyzed based on those patients who were taking statin drugs during the clinical trials and patients who were not taking statin drugs. Among all the patients, 276 (44%) patients were statin users and 348 (56%) did not use statins. Both groups had similar characteristics at baseline, but the statin users were on average older and had higher prevalence of cardiovascular disease. Continue reading